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Figure 3. Hematopoietic stem cell transplantation improves the high incidence of neutralizing allo-antibodies observed in Hurler's syndrome after pharmacological enzyme replacement therapy. J Comp Neurol. Enzyme cannot cross the blood—brain barrier; however, monocytes traffic from the blood into the brain where they differentiate into microglial cells and mediate cross-correction in the central nervous system.

Exp Neurol.

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Open in a separate window. Neuropsychological outcomes of several storage diseases with and without bone marrow transplantation. Bone marrow transplantation in mucopolysaccharidosis type IIIA: a comparison of an early treated patient with his untreated sibling.

Genetics sex linked inheritance video in Weybridge

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