We started by considering a pair of populations, one of West African ancestry YRI and one of northwestern European ancestry CEUwhich are the two populations we analyzed previously on the basis of the pilot data from the Genomes Project. A high-resolution recombination map of the human genome.
PLoS Genet. However, because our method relies on the unique mapping of reads, any sequences that occur in multiple locations in the genome could lead to spurious results. There is particular interest in fully annotating the avian W because the sex-determining mechanism in birds has yet to be completely characterized.
Certain parts of this website offer the opportunity for users to post opinions, information and material including without limitation academic papers and data 'Material' in areas distinguish sex chromosome and autosomes in Coventry the website.
We summarize alignment results for each contig using both the number of unmasked bases covered by a read coverage and a normalized measure of total number of reads aligned read depth; Figure 1 B. The W contigs form a distinct cluster from the autosomal or Z contigs. Alan E.
B Alignment results were summarized by two statistics: coverage and read depth. Material and Methods Population-Scale Sequence Data and SNP Calling In order to characterize and contrast patterns of diversity between X and the autosomes in a wide distinguish sex chromosome and autosomes in Coventry of global populations, we turned to the rich catalog of SNP and genotype calls released by phase 1 of the Genomes Project see Web Resources.
Each W-specific contig should have very few male-derived reads uniquely aligning to it.
Hudson R. Both measures should be near zero for W-specific contigs but not for autosomal or Z-linked contigs Figure 1 C. We used independent tests to further investigate the effects of contig length and sample imbalance on the predictive accuracy of our classifier.