Distinguish sex chromosome and autosomes in Coventry

We started by considering a pair of populations, one of West African ancestry YRI and one of northwestern European ancestry CEUwhich are the two populations we analyzed previously on the basis of the pilot data from the Genomes Project. A high-resolution recombination map of the human genome.

PLoS Genet. However, because our method relies on the unique mapping of reads, any sequences that occur in multiple locations in the genome could lead to spurious results. There is particular interest in fully annotating the avian W because the sex-determining mechanism in birds has yet to be completely characterized.

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distinguish sex chromosome and autosomes in Coventry

We summarize alignment results for each contig using both the number of unmasked bases covered by a read coverage and a normalized measure of total number of reads aligned read depth; Figure 1 B. The W contigs form a distinct cluster from the autosomal or Z contigs. Alan E.

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B Alignment results were summarized by two statistics: coverage and read depth. Material and Methods Population-Scale Sequence Data and SNP Calling In order to characterize and contrast patterns of diversity between X and the autosomes in a wide distinguish sex chromosome and autosomes in Coventry of global populations, we turned to the rich catalog of SNP and genotype calls released by phase 1 of the Genomes Project see Web Resources.

Each W-specific contig should have very few male-derived reads uniquely aligning to it.

  • The main difference between Autosomes and Sex Chromosomes is that Autosomes are usually taken part in defining the somatic types of an organism, whereas, Sex Chromosomes are generally taken part in establishing the sex of an individual and sex-linked hormonal characters. Autosomes usually determine the characters of an individual, and all males and females consist of some type of autosomes; on the other hand, sex chromosomes typically determine the gender of an individual, and all males and females contain different sex chromosomes according to their form, size, and behavior.
  • The chromosomes, apart from the sex chromosomes , are known as autosomes of an organism.
  • When we have a look at the basics definition, it tells us that an autosome is not a sex chromosome and that stands as the major difference between the two. So in this article, we are going to clarify the difference between an autosome and a sex chromosome.
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Hudson R. Both measures should be near zero for W-specific contigs but not for autosomal or Z-linked contigs Figure 1 C. We used independent tests to further investigate the effects of contig length and sample imbalance on the predictive accuracy of our classifier.

Distinguish sex chromosome and autosomes in Coventry

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