The Theory of the Free-Martin. Sex-specific differences in Utx expression depend on the complement of sex chromosomes To confirm that the higher expression of Utx in females is indeed caused by the presence of two expressed copies of the gene, we compared Utx expression in gonadally intact adult mice between 12 and 14 months of age using the four core genotypes i.
Nat Neurosci. Maier W, et al.
Integrative structural, functional, and transcriptomic analyses of sex-biased brain organization in humans. Researchers have long observed consistent sex-based differences in subcortical brain structures in mice. Related Stories.
This correspondence with cortical expression of sex-chromosome genes is also consistent with findings from earlier mouse studies, suggesting that sex differences in brain anatomy may be due, at least in part, to genetic mechanisms that have been conserved throughout mammalian evolution.
Although the datasets had notable demographic and methodological differences, the researchers found that the overall pattern of sex-based differences in cortical volume was highly consistent. Feb 18, Scientists identify new cancer stem cell biomarkers that may help predict response to radiation therapy in breast cancer patients.
The researchers also compared the anatomical findings with data from more brain sex differences orbitofrontal cortex mice in Norman 11, functional neuroimaging brain sex differences orbitofrontal cortex mice in Norman.
Specifically, regions of the cortex with relatively high expression of sex-chromosome genes tended to have greater cortical volume in males than females.
We have chosen to focus on neuroanatomical differences in the rat because the biological significance and origins of these differences are much clearer than in humans. Disteche 1. Neural mechanisms of aggression. We will then present some findings that have challenged this view.
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. We also thank Dr. For comparison of gene brain sex differences orbitofrontal cortex mice in Norman in adult liver between wild-type males and females, four samples were tested in each sex and each sample was pooled from two mice.
Sex differences in stress responses have been observed see Verma et al, and stress directly affects decision making in humans see Starcke and Brand, Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory.
Here, we assessed the effects of the pharmacological stressor yohimbine in the performance of both male and female rats in decision making.